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发布于:2017-10-31 08:28:51  访问:7 次 回复:0 篇
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What Kind Of Plant Is Forskolin
Actually, I think he discovered forskolin before he discovered Garcinia, but the forskolin propaganda seems to have reached a critical mass in the last few weeks.
The Land of Oz
A Dr. Oz episode on the “Rapid Belly Melt” aired a month ago, on May 5. He set fire to a paper representation of a fat belly to show how forskolin “works like a furnace inside your body.” The paper ignited, went up in flames, and revealed a non-flammable model of muscle tissue inside to show how forskolin burns fat, not muscle, and to illustrate how quickly it works.
In an earlier episode, in January, he called forskolin “lightning in a bottle,” and a “miracle flower to fight fat.” His guest, a weight loss expert, claimed it had doubled the weight loss of her clients. She said “if your metabolism is sleeping, forskolin is gonna wake it up.” She doesn’t claim that it will work miracles all by itself, but recommends it as an addition to gentle exercise and “cleaning up the diet”.
Dr. Oz says he pulled up all the research and was impressed by the evidence that it “ignites your metabolism.” He illustrates this metaphorically by throwing a white powder into a pot of simmering water, causing it to instantly start boiling vigorously.
The Land of Evidence
Dr. Oz is easy to impress. He cites a randomized placebo-controlled double blind trial of forskolin. It was a small preliminary study of obese or overweight men; there were only 15 men in each group, and the study lasted for 12 weeks. The subjects on forskolin showed favorable changes in body composition: a significant decrease in body fat percentage and fat mass, with a trend (non-significant) toward increased bone mass and lean body mass. Serum free testosterone levels were also significantly increased.
The details of the study are not important. What’s important is that the subjects taking forskolin did not lose weight. Even without weight loss, the changes in body composition are likely beneficial, but the increase in testosterone could be dangerous. Whatever the unresolved questions about benefits and risks, it is obviously misleading to cite this study as evidence that forskolin has been proven to melt belly fat or improve weight loss.
Another double blind study of 23 mildly overweight women, showed that forskolin had no significant effects on body composition and concluded that it “does not appear to promote weight loss but may help mitigate weight gain in overweight females with apparently no clinical significant side effects.”
Those are the only two studies in humans. Supplement Geek has written an analysis of some of the flaws in those studies that I won’t get into here. The only other pertinent research I could find was a study in rats suggesting that it may be effective in preventing diet-induced obesity. In rats.
What is it?
Forskolin is an herbal extract from Coleus forskohlii, a plant belonging to the mint family. Its mechanism of action? It increases the production of cyclic AMP, which increases the contractility of heart muscle. Evidence for other actions is preliminary and inconclusive: there is speculation that it may have effects in other cells of the body such as platelet and thyroid cells, it may prevent platelet aggregation and adhesions, and it might even prevent tumor cell growth and cancer metastasis.
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